教育及工作背景
2023/07-至今,汕头大学,数学与计算机学院,副教授
2021/02-2023/06,汕头大学,工学院,副教授
2018/09-2021/01广州中医药大学中西医结合基础研究中心,博士后
2013/09-2018/06广州中医药大学科技创新中心,博士
2009/09-2013/06河南大学计算机科学与技术专业,学士
主讲课程
本科生:《计算思维与工程伦理》《生物与医学信息大数据》
研究生:《工程伦理》
代表性项目
1.国家自然科学基金-面上项目. 知识图谱驱动下AD中医证候-内表型动态关联建模及“方-证-法”映射机制研究. (2026.01-2029.12). 48万元. 主持,在研
2. 国家自然科学基金-青年科学基金项目. 基于深度学习的中药心脏毒性预测及系统毒理学机制研究. (2020.01-2022.12). 24万元. 主持,已结题
3. 广东省自然科学基金-青年提升项目. 基于多模态异构生物分子网络的中药配伍减毒多层级科学内涵研究. (2024.01-2026.12). 30万元. 主持,在研
4. 广东省自然科学基金-面上项目. 深度学习与网络近邻法融合的中药心脏毒性预测框架及其应用. (2023.01-2025.12). 10万元. 主持,已结题
5. 广东省普通高校重点领域专项-生物医药与健康(食品)重点领域项目. 基于知识图谱驱动的“内表型-证候”联合网络框架探究抗AD创新中药方剂的发现与优化. (2024.10-2027.10). 30万元. 主持,在研
6. 中国博士后科学基金面上资助项目. 基于多任务深层网络的中药心血管安全性评价平台的构建 (2019.11-2021.01). 8万元. 主持,已结题
7. 汕头大学“卓越人才”计划优秀青年人才科研项目. 基于网络距离邻近算法的药物毒性研究 (2021.07-2024.06). 50万元. 主持
8. 教育部高等学校大学计算机课程教学指导委员会项目. 面向“整合思维”的大学计算机通识课程混合式教学模式改革. (2023.11-2024.11). 教改项目,主持
9. 汕头大学高等教育教学改革项目. 面向赋能教育与整合计算思维的大学计算机应用基础课程教学改革. (2023.11-2025.10). 教改项目,主持
代表性论文
1.Cai, C., Chen, Z., Wang, Z., Wu, L., Liu, Z., Fang, J.*, Liu, A.* (2026) ADMETPred: A High-Throughput ADMET Prediction Platform Integrating Multi-Model Algorithms and Interpretable Substructure Identification. Sci. China Life Sci. 69, 1–17. (IF=9.5,中科院一区top)
2.Wu, Q.#, Chen, Z.#, Wang, W., Wang, F., Chen, Z., Chi, J., Huang, J., Gu, Y.*, Fang, J*. and Cai, C*. (2026) Hepatotoxicity Prediction for Traditional Chinese Medicine: A Two-step in silico Framework Integrating Network and Machine Learning Approaches. BMC Complement Med Ther 26(1), 177. (corresponding author, IF = 3.4, 中科院二区)
3.Li, D.#, Cai, C.#, Liao, Y.#, Wu, Q., Ke, H., Guo, P., Wang, Q., Ding, B., Fang, J. * and Fang, S. * (2021) Systems pharmacology approach uncovers the therapeutic mechanism of medicarpin against scopolamine-induced memory loss. Phytomedicine 91, 153662. (co-first author, IF = 8.3,中科院一区top)
4.Dai, Z., Pang, X., Chen, N., Fan, X., Liu, W., Liu J., Chen, Z., Fang S., Cai, C.* Fang, J.* (2024) Network Medicine Approach Unravels Endophenotype Signature in Alzheimer’s Disease through Large-scale Comparative Proteomics Analysis: Vascular Dysfunction as a Prime Example. J Chem Inf Model. 64(19):7758-7771. (corresponding author, IF=5.3,中科院二区top)
5.Cai, C., Guo, P., Zhou, Y., Zhou, J., Wang, Q., Zhang, F., Fang, J. * and Cheng, F. * (2019) Deep Learning-Based Prediction of Drug-Induced Cardiotoxicity. J Chem Inf Model 59(3), 1073-1084. (IF=5.3,中科院二区top)
6.Zhou, C#. Cai, C.#, Huang, X., Wu, S., Yu, J., Wu, J., Fang, J.,* Li, G.*. (2024) TarKG: A Comprehensive Biomedical Knowledge Graph for Target Discovery. Bioinformatics. 40(10):btae598. (co-first author, CCF-A类推荐期刊)
7.Cai, C., Fang, J. *, Guo, P., Wang, Q., Hong, H., Moslehi, J. and Cheng, F*. (2018) In Silico Pharmacoepidemiologic Evaluation of Drug-Induced Cardiovascular Complications Using Combined Classifiers. J Chem Inf Model 58(5), 943-956. (IF=5.3,中科院二区top)
8.Wu, Q.#, Chen, Y.#, Gu, Y., Fang, S., Li, W., Wang, Q.*, Fang, J*. and Cai, C*. (2020) Systems pharmacology-based approach to investigate the mechanisms of Danggui-Shaoyao-san prescription for treatment of Alzheimer's disease. BMC Complement Med Ther 20(1), 282. (corresponding author,中科院二区)
9.Cai, C., Xu, L., Fang, J., Dai, Z., Wu, Q., Liu, X., Wang, Q., Fang, J.*, Liu, A.L. * and Du, G.H. * (2021) In Silico Prediction and Bioactivity Evaluation of Chemical Ingredients Against Influenza A Virus From Isatis tinctoria L. Front Pharmacol 12, 755396.
10.Wu, Q.#, Fan, X.#, Hong, H.#, Gu, Y., Liu, Z., Fang, S., Wang, Q., Cai, C*. and Fang, J*. (2020) Comprehensive assessment of side effects in COVID-19 drug pipeline from a network perspective. Food Chem Toxicol 145, 111767. (corresponding author)
ORCID ID
https://orcid.org/0000-0002-6778-9697